VS 2008 Is there a way to monitor a port by program/application/service name?

I have found plenty of code samples that will open a port (TCP/UDP), but what I'm wanting to do is monitor a port by application that may or may not already be open between two programs.

How would I go about checking to see if a port connection has already been made between two programs, particularly if the port isn't always the same?

Also, this particular program (service) can be connected to hundreds of clients... I'll need to monitor them all. Is that possible?

Thanks,
-Shooter